PUBLICATIONS

SL. Mixed Amide Paracyclophane Assemblies Emulating Supramolecular Copolymers. Cole D. Stearns,† Ajeet Kumar,† Ion Ghiviriga, Lukasz M. Dobrzycki, Khalil A. Abboud, and Ronald K. Castellano*. J. Am. Chem. Soc. 2025, 147, 24615.

SL. Non-Canonical, Strongly Selective Protein Disulfide Isomerases as Anticancer Therapeutic Targets. Mary E. Law,† Zaafir M. Dulloo,† Brian Hardy, Ania Kelegama, Reagan Clark, Mariana Rivas Montbrun, Gabriella Antmann, Srihith Nooka, Ronald K. Castellano, and Brian K. Law*. Biomolecules 2025, 15, 1146.

SL. DR5 Disulfide Bonding Functions as a Sensor and Effector of Protein Folding Stress. ME Law,† ZM. Dulloo,† SR Eggleston, GP Takacs, GM Alexandrow, Y il Lee, M Wang, B Hardy, H Su, B Forsyth, P Das, PK Datta, CW Chiang, A Sharma, SRR Kanumuri, OA Guryanova, JK Harrison, B Tirosh, RK Castellano*, and BK Law*. Mol. Cancer Res. (2025) 23 (7): 622.

SL. Beta-cyclodextrin formulation of a disulfide-bond disrupting agent for improved systemic exposure. Zaafir M. Dulloo, Ion Ghiviriga, Mary E. Law, Sarvesh K. Verma, Abhisheak Sharma, Brian K. Law*, and Ronald K. Castellano*. RSC Med. Chem. 2025, 16, 3622.

SL. Diagnosing the role of hydrogen bonding in the organization, aggregation, and optical properties of phthalhydrazide-functionalized molecules in solution and solid state. Cheng-Yen Pan,† Nathan J. Grinalds,† Ion Ghiviriga, Khalil A. Abboud, Jiangeng Xue*, and Ronald K. Castellano*. New J. Chem. 2025, 49, 5330.

SL. 2-(1,1-Dicyanomethylene)rhodanine-Functionalized Oligothiophenes: A Structure–Property Investigation of Z/E Photoisomerization Behavior. Cory T. Kornman,† Parag Das,† Lei Li, Asmerom O. Weldeab, Ion Ghiviriga, and Ronald K. Castellano*. J. Org. Chem. 2024, 89, 13853.

SL. Structure–property relationships in dicyanopyrazinoquinoxalines and their hydrogen-bonding-capable dihydropyrazinoquinoxalinedione derivatives. Tural N. Akhmedov, Ajeet Kumar, Daken J. Starkenburg, Kyle J. Chesney, Khalil A. Abboud, Novruz G. Akhmedov, Jiangeng Xue, and Ronald K. Castellano*. Beilstein J. Org. Chem. 2024, 20, 1037.

SL. Dicyanorhodanine-Pyrrole Conjugates for Visible Light-Driven Quantitative Photoswitching in Solution and the Solid State. Parag Das, Nathan J. Grinalds, Ion Ghiviriga, Khalil A. Abboud, Łukasz Dobrzycki, Jiangeng Xue*, and Ronald K. Castellano*. J. Am. Chem. Soc. 2024, 146, 11932.

SL. A small molecule multi-FRET platform from benzotrifuranone. Ashton N. Bartley , Sadie F. DePeter, and Ronald K. Castellano*. Dyes and Pigments 220 (2023) 111732.

SL. Enlightening the Well-Controlled Photochemical Behavior of 1,1-Dicyanomethylene-3-Indanone-Functionalized π-Conjugated Molecules. Parag Das, Cory T. Kornman, Ion Ghiviriga, Khalil A. Abboud, and Ronald K. Castellano*. Chem. Mater. 2023, 35, 8122.

SL. Thin-Film Morphology and Optical Properties of Photoisomerizable Donor−Acceptor Oligothiophenes. David M. Camero, Nathan J. Grinalds, Cory T. Kornman, Stefano Barba, Lei Li, Asmerom O. Weldeab, Ronald K. Castellano,* and Jiangeng Xue*. ACS Appl. Mater. Interfaces 2023, 15, 25134.

SL. Inhibitors of ERp44, PDIA1, and AGR2 induce disulfide-mediated oligomerization of Death Receptors 4 and 5 and cancer cell death. Mary E Law, Elham Yaaghubi, Amanda F Ghilardi, Bradley J Davis, Renan B Ferreira, Jin Koh, Sixue Chen, Sadie F DePeter, Christopher M Schilson, Chi-Wu Chiang, Coy D Heldermon, Peter Nørgaard, Ronald K Castellano*, and Brian K Law*. Cancer Letters 534 (2022) 215604.

SL. Repurposing Tranexamic Acid as an Anticancer Agent. Mary E. Law, Bradley J. Davis, Amanda F. Ghilardi, Elham Yaaghubi, Zaafir M. Dulloo, Mengxiong Wang, Olga A. Guryanova, Coy D. Heldermon, Stephan C. Jahn, Ronald K. Castellano, and Brian K. Law*. Front. Pharmacol. 2022, 12, 792600.

SL. Anticancer
Agents Derived from Cyclic Thiosulfonates: Structure-Reactivity and Structure-Activity Relationships. Amanda F. Ghilardi,† Elham Yaaghubi,† Renan B. Ferreira, Mary E. Law, Yinuo Yang, Bradley J. Davis, Christopher M. Schilson, Ion Ghiviriga, Adrian E. Roitberg, Brian K. Law*, and Ronald K. Castellano*. ChemMedChem 2022, 17, e202200165.

SL. Tuning Supramolecular Polymer Assembly through Stereoelectronic Interactions. Will R. Henderson, Guancen Liu, Khalil A. Abboud, and Ronald K. Castellano*. J. Am. Chem. Soc. 2021, 143, 12688.

SL. Structure–Assembly–Property Relationships of Simple Ditopic Hydrogen-Bonding-Capable π-Conjugated Oligomers. Asmerom O. Weldeab , Cory T. Kornman , Lei Li , Daken J. Starkenburg, Xueying Zhao, Danielle E. Fagnani , Sara J. Sadovy, Scott S. Perry, Jiangeng Xue *, Ronald K. Castellano*. Organic Materials 2021, 3, 390.

SL. Supramolecular polymerization of chiral molecules devoid of chiral centers. Will R Henderson, and Ronald K Castellano*. Polym Int 2021; 70: 897.

SL. Influence of Amide Connectivity on the Hydrogen-Bond-Directed Self-Assembly of [n.n]Paracyclophanes. Will R. Henderson, Ajeet Kumar, Khalil A. Abboud, and Ronald K. Castellano*. Chem. Eur. J. 2020, 26, 17588.

SL. Photoisomerization of dicyanorhodanine-functionalized thiophenes. Cory T. Kornman,† Lei Li,† Asmerom O. Weldeab, Ion Ghiviriga, Khalil A. Abboud, and Ronald K. Castellano *. Chem. Sci. 2020, 11, 10190.

SL. Self-Assembling [n.n]Paracyclophanes: A Structure–Property Relationship Study. Will R. Henderson, Yu Zhu, Danielle E. Fagnani, Guancen Liu, Khalil A. Abboud, and Ronald K. Castellano*. J. Org. Chem. 2020, 85, 1158.

SL. Disulfide bond-disrupting agents activate the tumor necrosis family-related apoptosis-inducing ligand/death receptor 5 pathway. Mengxiong Wang, Mary E. Law, Bradley J. Davis, Elham Yaaghubi, Amanda F. Ghilardi, Renan B. Ferreira, Chi-Wu Chiang, Olga A. Guryanova, Daniel Kopinke, Coy D. Heldermon, Ronald K. Castellano*, and Brian K. Law*. Cell Death Discovery 2019, 5, 153.

SL. A metabolic switch in proteasome inhibitor-resistant multiple myeloma ensures higher mitochondrial metabolism, protein folding and sphingomyelin synthesis. Lenka Besse,† Andrej Besse,† Max Mendez-Lopez, Katerina Vasickova, Miroslava Sedlackova, Petr Vanhara, Marianne Kraus, Jürgen Bader ,Renan B. Ferreira, Ronald K. Castellano, Brian K. Law, and Christoph Driessen*. Haematologica 2019, 104, e415.

SL. A novel proteotoxic combination therapy for EGFR+ and HER2+ cancers. Mengxiong Wang, Renan B. Ferreira, Mary E. Law, Bradley J. Davis, Elham Yaaghubi, Amanda F. Ghilardi, Abhisheak Sharma, Bonnie A. Avery, Edgardo Rodriguez, Chi-Wu Chiang, Satya Narayan, Coy D. Heldermon, Ronald K. Castellano*, and Brian K. Law*. Oncogene 2019, 38, 4264.

SL. Transannular Hydrogen Bonding in Planar‐Chiral [2.2] Paracyclophane‐Bisamides. Will R. Henderson, Danielle E. Fagnani, Jonathan Grolms, Khalil A. Abboud, Ronald K. Castellano*. Helv. Chim. Acta 2019, 102, e1900047.

SL. Differentiating the mechanism of self-assembly in supramolecular polymers through computation. Divya B. Korlepara, Will R. Henderson, Ronald K. Castellano, and Sundaram Balasubramanian*. Chem. Commun. 2019, 55, 3773.

SL. Synthesis, Optoelectronic Properties, Self-Association, and Base Pairing of Nucleobase-Functionalized Oligothiophenes. Danielle E. Fagnani, Raghida Bou Zerdan, and Ronald K. Castellano*. J. Org. Chem. 2018, 83, 12711.

SL. The unfolded protein response as a target for anticancer therapeutics. Mengxiong Wang, Mary E Law, Ronald K Castellano, Brian K Law*. Critical Reviews in Oncology/Hematology 127 (2018) 66.

SL. Pyridine-terminated low gap π-conjugated oligomers: design, synthesis, and photophysical response to protonation and metalation. Asmerom O. Weldeab, Lei Li, Seda Cekli, Khalil A. Abboud, Kirk S. Schanze, and Ronald K. Castellano*. Org. Chem. Front. 2018, 5, 3170.

SL. Tuning the structural and spectroscopic properties of donor–acceptor–donor oligomers via mutual X-bonding, H-bonding, and pi–pi interactions. Asmerom O. Weldeab, April Steen, Daken J. Starkenburg, Jon Steven Dal Williams, Khalil A. Abboud, Jiangeng Xue, Nathan I. Hammer, Ronald K. Castellano*, and Davita L. Watkins*. J. Mater. Chem. C 2018, 6, 11992.

SL. Disulfide bond disrupting agents activate the unfolded protein response in EGFR- and HER2-positive breast tumor cells. Renan B. Ferreira, Mengxiong Wang, Mary E. Law, Bradley J. Davis, Ashton N. Bartley, Paul J. Higgins, Michael S. Kilberg, Katherine E. Santostefano, Naohiro Terada, Coy D. Heldermon, Ronald K. Castellano, and Brian K. Law*. Oncotarget 2017, 8, 28971.