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Department of Chemistry College of Liberal Arts and Sciences

PUBLICATIONS

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University of Florida (2002–present)

YearTOCPublication
2026Table of contents graphic for “Photochromism of Dicyanorhodanine-Pyrrole Conjugates: Substituent and Solvent Effects”Photochromism of Dicyanorhodanine-Pyrrole Conjugates: Substituent and Solvent Effects. Das, P.; Charles, S. M.; Bocchieri, A.; Dobrzycki, Ł.; Castellano, R. K.* ACS Omega 2026, 11, 45560–45573.
2026Table of contents graphic for “Supramolecular Arene-Perfluoroarene Assembly Enhances Photoiniferter Polymerization Kinetics”Supramolecular Arene-Perfluoroarene Assembly Enhances Photoiniferter Polymerization Kinetics. Marquez, J. D.†; Stearns, C. D.†; Stewart, K. A.; Gilchrist, G. C.; Ghiviriga, I.; Bailey, L. S.; Sumerlin, B. S.*; Castellano, R. K.*; Evans, A. E.* Angew. Chem. Int. Ed. 2026, 65, e5251809.
2026Table of contents graphic for “[2.2]Paracyclophane-Dicyanorhodanine Conjugates as Planar Chiral Molecular Photoswitches”[2.2]Paracyclophane-Dicyanorhodanine Conjugates as Planar Chiral Molecular Photoswitches. Das, P.; Stearns, C. D.; Ghiviriga, I.; Dobrzycki, Ł.; Castellano, R. K.* Org. Chem. Front. 2026, 13, 764–776.
2025Table of contents graphic for “Non-Canonical, Strongly Selective Protein Disulfide Isomerases as Anticancer Therapeutic Targets”Non-Canonical, Strongly Selective Protein Disulfide Isomerases as Anticancer Therapeutic Targets. Law, M. E.†; Dulloo, Z. M.†; Hardy, B.; Kelegama, A.; Clark, R.; Montbrun, M. R.; Antmann, G.; Nooka, S.; Castellano, R. K.; Law, B. K.* Biomolecules 2025, 15, 1146.
2025Table of contents graphic for “Mixed Amide [2.2]Paracyclophane Assemblies Emulating Supramolecular Copolymers”Mixed Amide [2.2]Paracyclophane Assemblies Emulating Supramolecular Copolymers. Stearns, C. D.†; Kumar, A.†; Ghiviriga, I.; Dobrzycki, Ł.; Abboud, K. A.; Castellano, R. K.* J. Am. Chem. Soc. 2025, 147, 24615–24627.
2025Table of contents graphic for “Beta-Cyclodextrin Formulation of a Disulfide-Bond Disrupting Agent for Improved Systemic Exposure”Beta-Cyclodextrin Formulation of a Disulfide-Bond Disrupting Agent for Improved Systemic Exposure. Dulloo, Z. M.; Ghiviriga, I.; Law, M. E.; Verma, S. K.; Sharma, A.; Law, B. K.*; Castellano, R. K.* RSC Med. Chem. 2025, 16, 3622–3632.
2025Table of contents graphic for “DR5 Disulfide Bonding Functions as a Sensor and Effector of Protein Folding Stress”DR5 Disulfide Bonding Functions as a Sensor and Effector of Protein Folding Stress. Law, M. E.†; Dulloo, Z. M.†; Eggleston, S. R.; Takacs, G. P.; Alexandrow, G. M.; il Lee, Y.; Wang, M.; Hardy, B.; Su, H.; Forsyth, B.; Das, P.; Datta, P. K.; Chiang, C.-W.; Sharma, A.; Kanumuri, S. R. R.; Guryanova, O. A.; Harrison, J. K.; Tirosh, B.; Castellano, R. K.*; Law, B. K.* Mol. Cancer Res. 2025, 23, 622–639.
2025Table of contents graphic for “Hydrogen Bonding Mediated Self-Assembly of Strongly Aggregating Quinoxaline-Phthalhydrazide Conjugates: Optoelectronic Properties in Solution and the Solid State”Hydrogen Bonding Mediated Self-Assembly of Strongly Aggregating Quinoxaline-Phthalhydrazide Conjugates: Optoelectronic Properties in Solution and the Solid State. Pan, C.-Y.†; Grinalds, N. J.†; Ghiviriga, I.; Abboud, K. A.; Xue, J.*; Castellano, R. K.* New J. Chem. 2025, 49, 5330–5345.
2025US Must Support Chemistry Research. Allen, K., et al. Science 2025, 1282–1283. (letter)
2024Table of contents graphic for “2-(1,1-Dicyanomethylene)rhodanine-Functionalized Oligothiophenes: A Structure-Property Investigation of Z/E Photoisomerization Behavior”2-(1,1-Dicyanomethylene)rhodanine-Functionalized Oligothiophenes: A Structure-Property Investigation of Z/E Photoisomerization Behavior. Kornman, C. T.†; Das, P.†; Li, L.; Weldeab, A. O.; Ghiviriga, I.; Castellano, R. K.* J. Org. Chem. 2024, 89, 13853–13867.
2024Table of contents graphic for “Structure-Property Relationships in Dicyanopyrazinoquinoxalines and Their Derivative Hydrogen-Bonding-Capable Dihydropyrazinoquinoxalinediones”Structure-Property Relationships in Dicyanopyrazinoquinoxalines and Their Derivative Hydrogen-Bonding-Capable Dihydropyrazinoquinoxalinediones. Akhmedov, T. N.; Kumar, A.; Starkenburg, D. J.; Chesney, K. J.; Abboud, K. A.; Akhmedov, N. G.; Xue, J.; Castellano, R. K.* Beilstein J. Org. Chem. 2024, 20, 1037–1052.
2024Table of contents graphic for “Dicyanorhodanine-Pyrrole Conjugates for Visible-Light-Driven Quantitative Photoswitching in Solution and the Solid State”Dicyanorhodanine-Pyrrole Conjugates for Visible-Light-Driven Quantitative Photoswitching in Solution and the Solid State. Das, P.; Grinalds, N. J.; Ghiviriga, I.; Abboud, K. A.; Dobrzycki, Ł.; Xue, J.*; Castellano, R. K.* J. Am. Chem. Soc. 2024, 146, 11932–11943.
2023Table of contents graphic for “A Small Molecule Multi-FRET Platform from Benzotrifuranone”A Small Molecule Multi-FRET Platform from Benzotrifuranone. Bartley, A. N.; DePeter, S. F.; Castellano, R. K.* Dyes Pigm. 2023, 220, 111732.
2023Table of contents graphic for “Enlightening the Well-Controlled Photochemical Behavior of 1,1-Dicyanomethylene-3-Indanone-Functionalized π-Conjugated Molecules”Enlightening the Well-Controlled Photochemical Behavior of 1,1-Dicyanomethylene-3-Indanone-Functionalized π-Conjugated Molecules. Das, P.; Kornman, C. T.; Ghiviriga, I.; Abboud, K. A.; Castellano, R. K.* Chem. Mater. 2023, 35, 8122–8134.
2023Table of contents graphic for “Thin-Film Morphology and Optical Properties of Photo-isomerizable Donor-Acceptor Oligothiophenes”Thin-Film Morphology and Optical Properties of Photo-isomerizable Donor-Acceptor Oligothiophenes. Camero, D. M.; Grinalds, N. J.; Kornman, C. T.; Barba, S.; Li, L.; Weldeab, A. O.; Castellano, R. K.*; Xue, J.* ACS Appl. Mater. Interfaces 2023, 15, 25134–25147.
2022Table of contents graphic for “Anticancer Agents Derived from Cyclic Thiosulfonates: Structure-Reactivity and Structure-Activity Relationships”Anticancer Agents Derived from Cyclic Thiosulfonates: Structure-Reactivity and Structure-Activity Relationships. Ghilardi, A. F.†; Yaaghubi, E.†; Ferriera, R. B.; Law, M. E.; Davis, B. J.; Schilson, C. M.; Ghiviriga, I.; Law, B. K.*; Castellano, R. K.* ChemMedChem 2022, 17, e202200165.
2022Table of contents graphic for “Inhibitors of ERp44, PDIA1, and AGR2 Induce Disulfide-Mediated Oligomerization of Death Receptors 4 and 5 and Cancer Cell Death”Inhibitors of ERp44, PDIA1, and AGR2 Induce Disulfide-Mediated Oligomerization of Death Receptors 4 and 5 and Cancer Cell Death. Law, M. E.; Yaaghubi, E.; Ghilardi, A. F.; Davis, B. J.; Ferriera, R. B.; Koh, J.; Chen, S.; DePeter, S. F.; Schilson, C. M.; Chiang, C.-W.; Heldermon, C.; Nørgaard, P.; Castellano, R. K.*; Law, B. K.* Cancer Lett. 2022, 534, 215604.
2022Repurposing Tranexamic Acid as an Anticancer Agent. Law, M. E.; Davis, B. J.; Ghilardi, A. F.; Yaaghubi, E.; Dulloo, Z. M.; Wang, M.; Guryanova, O. A.; Heldermon, C. D.; Jahn, S. C.; Castellano, R. K.; Law, B. K.* Front. Pharmacol. 2022, 12, 792600.
2022Editorial: Suprastars of Chemistry. Xiao, T.; James, T. D.; Borovkov, V.; Castellano, R. K.; Deng, C. Front. Chem. 2022, 10, online. (editorial)
2021Table of contents graphic for “Tuning Supramolecular Polymer Assembly Through Stereoelectronic Interactions”Tuning Supramolecular Polymer Assembly Through Stereoelectronic Interactions. Henderson, W. R.; Liu, G.; Abboud, K. A.; Castellano, R. K.* J. Am. Chem. Soc. 2021, 143, 12688–12698.
2021Table of contents graphic for “Structure-Assembly-Property Relationships of Simple Ditopic Hydrogen Bonding-Capable π-Conjugated Oligomers”Structure-Assembly-Property Relationships of Simple Ditopic Hydrogen Bonding-Capable π-Conjugated Oligomers. Weldeab, A. O.; Kornman, C. T.; Li, L.; Starkenburg, D. J.; Zhao, X.; Fagnani, D. E.; Sadovy, S. J.; Perry, S. S.; Xue, J.*; Castellano, R. K.* Organic Materials 2021, 3, 390–404.
2021Table of contents graphic for “Supramolecular Polymerization of Chiral Molecules Devoid of Chiral Centers”Supramolecular Polymerization of Chiral Molecules Devoid of Chiral Centers. Henderson, W. R.; Castellano, R. K.* Polym. Int. 2021, 70, 897–910.
2020Table of contents graphic for “Influence of Amide Connectivity on the Hydrogen Bond Directed Self-Assembly of [n.n]Paracyclophanes”Influence of Amide Connectivity on the Hydrogen Bond Directed Self-Assembly of [n.n]Paracyclophanes. Henderson, W. R.; Kumar, A.; Abboud, K. A.; Castellano, R. K.* Chem. Eur. J. 2020, 26, 17588–17597.
2020Table of contents graphic for “Photoisomerization of Dicyanorhodanine-Functionalized Thiophenes”Photoisomerization of Dicyanorhodanine-Functionalized Thiophenes. Kornman, C. T.†; Li, L.†; Weldeab, A. O.; Ghiviriga, I.; Abboud, K. A.; Castellano, R. K.* Chem. Sci. 2020, 11, 10190–10197.
2020Table of contents graphic for “Consequence of Monomer Dynamics on the Homochiral Self-Assembly of [n.n]Paracyclophanes”Consequence of Monomer Dynamics on the Homochiral Self-Assembly of [n.n]Paracyclophanes. Henderson, W. R.; Zhu, Y.; Fagnani, D. E.; Liu, G.; Abboud, K. A.; Castellano, R. K.* J. Org. Chem. 2020, 85, 1158–1167.
2019Disulfide Bond Disrupting Agents Activate the Tumor Necrosis Family-Related Apoptosis-Inducing Ligand/Death Receptor 5 Pathway. Wang, M.; Ferreira, R. B.; Law, M. E.; Davis, B. J.; Yaaghubi, E.; Ghilardi, A. F.; Rodriguez, E.; Chiang, C.-W.; Narayan, S.; Heldermon, C.; Castellano, R. K.*; Law, B. K.* Cell Death Discov. 2019, 5, 153.
2019Transannular Hydrogen Bonding in Regioisomeric [2.2]Paracyclophane-bisamides. Henderson, W. R.; Fagnani, D. E.; Grolms, J.; Abboud, K. A.; Castellano, R. K.* Helv. Chim. Acta 2019, 102, e1900047.
2019Table of contents graphic for “Differentiating the Mechanism of Self-Assembly in Supramolecular Polymers through Computation”Differentiating the Mechanism of Self-Assembly in Supramolecular Polymers through Computation. Korlepara, D. B.; Henderson, W. R.; Castellano, R. K.; Balasubramanian, S.* Chem. Commun. 2019, 55, 3773–3776.
2019A Metabolic Switch in Proteasome Inhibitor Resistant Multiple Myeloma Ensures Higher Mitochondrial Metabolism, Protein Folding and Sphingomyelin Synthesis. Besse, L.*; Besse, A.; Mendez-Lopez, M.; Vasickova, K.; Sedlackova, M.; Vanhara, P.; Kraus, M.; Bader, J.; Ferreira, R. B.; Castellano, R. K.; Law, B. K.; Driessem, C. Haematologica 2019, 104, e415-e419.
2019A Novel Proteotoxic Combination Therapy for EGFR+ and HER2+ Cancers. Wang, M.; Ferreira, R. B.; Law, M. E.; Davis, B. J.; Yaaghubi, E.; Ghilardi, A. F.; Sharma, A.; Avery, B. A.; Rodriguez, E.; Chiang, C.-W.; Narayan, S.; Heldermon, C.; Castellano, R. K.*; Law, B. K.* Oncogene 2019, 38, 4264-4282.
2018Table of contents graphic for “Pyridine-Terminated Low Gap π-Conjugated Oligomers: Design, Synthesis, and Photophysical Response to Protonation and Metalation”Pyridine-Terminated Low Gap π-Conjugated Oligomers: Design, Synthesis, and Photophysical Response to Protonation and Metalation. Weldeab, A. O.; Li, L.; Cekli, S.; Abboud, K. A.; Schanze, K. S.; Castellano, R. K.* Org. Chem. Front. 2018, 5, 3170–3177 (special collection in honor of Prof. Julius Rebek, Jr.).
2018Table of contents graphic for “Synthesis, Optoelectronic Properties, Self-Association, and Base Pairing of Nucleobase Functionalized Oligothiophenes”Synthesis, Optoelectronic Properties, Self-Association, and Base Pairing of Nucleobase Functionalized Oligothiophenes. Fagnani, D. E.; Bou Zerdan, R.; Castellano, R. K.* J. Org. Chem. 2018, 83, 12711–12721.
2018Table of contents graphic for “Tuning the Structural and Spectroscopic Properties of Donor-Acceptor-Donor Oligomers via Mutual X-Bonding, H-Bonding, and π-π Interactions”Tuning the Structural and Spectroscopic Properties of Donor-Acceptor-Donor Oligomers via Mutual X-Bonding, H-Bonding, and π-π Interactions. Weldeab, A. O.; Steen, A.; Starkenburg, D. J.; Williams, J. S. D.; Abboud, K. A.; Xue, J.; Hammer, N. I.; Castellano, R. K.*; Watkins, D. L.* J. Mater. Chem. C 2018, 6, 11992–12000.
2018The Unfolded Protein Response as a Target for Anticancer Therapeutics. Wang, M.; Law, M. E.; Castellano, R. K.; Law, B. K.* Crit. Rev. Oncol. Hematol. 2018, 127, 66–79.
2017Table of contents graphic for “Benzotrifuran (BTFuran): A Building Block for π-Conjugated Systems”Benzotrifuran (BTFuran): A Building Block for π-Conjugated Systems. Ferreira, R. B.; Figueroa, J. M.; Fagnani, D. E.; Abboud, K. A.; Castellano, R. K.* Chem. Commun. 2017, 53, 9590–9593.
2017Table of contents graphic for “Ambient-Temperature Synthesis of ω,ω-Heterodifunctionalized Polymers and Polymeric Bioconjugates”Ambient-Temperature Synthesis of ω,ω-Heterodifunctionalized Polymers and Polymeric Bioconjugates. Figg, C. A.; Bartley, A. N.; Kubo, T.; Tucker, B. S.; Castellano, R. K.*; Sumerlin, B. S.* Polym. Chem. 2017, 8, 2457–2461 (journal cover art and “Best Paper of the Month”, April 2017).
2017Table of contents graphic for “Disulfide Bond Disrupting Agents Activate the Unfolded Protein Response in EGFR- and HER2-Positive Breast Tumor Cells”Disulfide Bond Disrupting Agents Activate the Unfolded Protein Response in EGFR- and HER2-Positive Breast Tumor Cells. Ferreira, R. B.†; Wang, M.†; Law, M. E.; Davis, B. J.; Bartley, A. N.; Higgins, P. J.; Kilberg, M. S.; Santostefano, K. E.; Terada, N.; Heldermon, C. D.; Castellano, R. K.*; Law, B. K.* Oncotarget 2017, 8, 28971–28989.
2017Table of contents graphic for “π–π Interactions”π–π Interactions. Fagnani, D. E.; Sotuyo, A.; Castellano, R. K. In Comprehensive Supramolecular Chemistry II, Atwood, J. L., Ed.; Elsevier: Oxford, 2017, 1, 121–148. (book chapter)
2016Table of contents graphic for “The Selective and Sequential Aminolysis of Benzotrifuranone: A Synergism of Electronic Effects and a Ring Strain Gradient”The Selective and Sequential Aminolysis of Benzotrifuranone: A Synergism of Electronic Effects and a Ring Strain Gradient. Baker, M. B.; Tasseroul, J.; Ferreira, R. B.; Lampkins, A. J.; Al Abbas, A.; Abboud, K. A.; Castellano, R. K.* J. Org. Chem. 2016, 81, 9279–9288.
2016Table of contents graphic for “Homochiral [2.2]Paracyclophane Self-Assembly Promoted by Transannular Hydrogen Bonding”Homochiral [2.2]Paracyclophane Self-Assembly Promoted by Transannular Hydrogen Bonding. Fagnani, D. E.; Meese, M. J., Jr.; Abboud, K. A.; Castellano, R. K.* Angew. Chem. Int. Ed. 2016, 55, 10726–10731.
2016CUB Domain-Containing Protein 1 and the Epidermal Growth Factor Receptor Cooperate to Induce Cell Detachment. Law, M. E.; Ferreira, R. B.; Davis, B. J.; Higgins, P. J.; Kim, J.-S.; Castellano, R. K.; Chen, S.; Luesch, H.; Law, B. K.* Breast Cancer Res. 2016, 18:80, 1–17.
2016Meet Our Regional Editor. Castellano, R. K. Curr. Org. Chem. 2016, 20, 1. (editorial)
2015ACE2/Ang-(1-7)/Mas Axis Stimulates Vascular Repair-Relevant Functions of CD34+ Cells. Singh, N.; Joshi, S.; Guo, L.; Baker, M. B.; Li, Y.; Castellano, R. K.; Raizada, M. K.; Jarajapu, Y. P. R.* Am. J. Physiol. Heart Circ. Physiol. 2015, 309, H1697–H1707.
2015Table of contents graphic for “Enhancement in Organic Photovoltaic Efficiency through the Synergistic Interplay of Molecular Donor Hydrogen Bonding and π-Stacking”Enhancement in Organic Photovoltaic Efficiency through the Synergistic Interplay of Molecular Donor Hydrogen Bonding and π-Stacking. Shewmon, N. T.; Watkins, D. L.; Galindo, J.; Bou Zerdan, R.; Chen, J.; Keum, J.; Roitberg, A. E.; Xue, J.*; Castellano, R. K.* Adv. Funct. Mater. 2015, 25, 5166–5177.
2015Table of contents graphic for “Novel Agents That Downregulate EGFR, HER2, and HER3 in Parallel”Novel Agents That Downregulate EGFR, HER2, and HER3 in Parallel. Ferreira, R. B.; Law, M. E.; Jahn, S. C.; Davis, B. J.; Heldermon, C. D.; Reinhard, M. K.; Castellano, R. K.*; Law, B. K.* Oncotarget 2015, 6, 10445–10459.
2015Table of contents graphic for “Hydrogen Bond Directed Assembly of Oligothiophene/Fullerene Superstructures on Au(111)”Hydrogen Bond Directed Assembly of Oligothiophene/Fullerene Superstructures on Au(111). Zhao, X.; Watkins, D. L.; Galindo, J.; Shewmon, N. T.; Roitberg, A. E.; Xue, J.*; Castellano, R. K.*; Perry, S. S.* Org. Electron. 2015, 19, 61–69.
2015Table of contents graphic for “Synthesis, Optical Properties, and Electronic Structures of Nucleobase-Containing π-Conjugated Oligomers”Synthesis, Optical Properties, and Electronic Structures of Nucleobase-Containing π-Conjugated Oligomers. Bou Zerdan, R.; Cohn, P.; Puodziukynaite, E.; Baker, M. B.; Voisin, M.; Sarun, C.; Castellano, R. K.* J. Org. Chem. 2015, 80, 1828–1840.
2014Table of contents graphic for “Estimating the Shape and Size of Supramolecular Assemblies by Variable Temperature Diffusion Ordered Spectroscopy”Estimating the Shape and Size of Supramolecular Assemblies by Variable Temperature Diffusion Ordered Spectroscopy. Schulze, B. M.; Watkins, D. L.; Zhang, J.; Ghiviriga, I.; Castellano, R. K.* Org. Biomol. Chem. 2014, 12, 7932-7936.
2014Table of contents graphic for “The Influence of Solubilizing Chain Stereochemistry on Small Molecule Photovoltaics”The Influence of Solubilizing Chain Stereochemistry on Small Molecule Photovoltaics. Bou Zerdan, R.†; Shewmon, N. T.†; Zhu, Y.; Mudrick, J. P.; Chesney, K. J.; Xue, J.*; Castellano, R. K.* Adv. Funct. Mater. 2014, 24, 5993–6004.
2014Table of contents graphic for “Consequences of Hydrogen Bonding on Molecular Organization and Device Performance in Molecular Organic Photovoltaic Cells”Consequences of Hydrogen Bonding on Molecular Organization and Device Performance in Molecular Organic Photovoltaic Cells. Schulze, B. M.†; Shewmon, N. T.†; Zhang, J.; Watkins, D. L.; Mudrick, J. P.; Cao, W.; Bou Zerdan, R.; Quartararo, A. J.; Ghiviriga, I.; Xue, J.*; Castellano, R. K.* J. Mater. Chem. A 2014, 2, 1541–1549.
2014Special Issue: Intramolecular Hydrogen Bonding. Castellano, R. K. Molecules 2014, 19, 15783–15785. (editorial)
2013Table of contents graphic for “Ultraviolet–violet Electroluminescence from Highly Fluorescent Purines”Ultraviolet–violet Electroluminescence from Highly Fluorescent Purines. Yang, Y.; Cohn, P.; Eom, S.-H.; Abboud, K. A.; Castellano, R. K.*; Xue, J.* J. Mater. Chem. C 2013, 1, 2867–2874.
2012Table of contents graphic for “Seven-Membered Intramolecular Hydrogen Bonding of Phenols: Database Analysis and Phloroglucinol Model Compounds”Seven-Membered Intramolecular Hydrogen Bonding of Phenols: Database Analysis and Phloroglucinol Model Compounds. Castellano, R. K.*; Li, Y.; Homan, E. A.; Lampkins, A. J.; Marín, I. V.; Abboud, K. A. Eur. J. Org. Chem. 2012, 2012, 4483–4492.
2012Table of contents graphic for “Molecular Multifunctionalization via Electronically Coupled Lactones”Molecular Multifunctionalization via Electronically Coupled Lactones. Baker, M. B.; Ghiviriga, I.; Castellano, R. K.* Chem. Sci. 2012, 3, 1095–1099.
2011Table of contents graphic for “Self-Assembled Amphiphilic Diketopyrrolopyrrole-Based Oligothiophenes for Field-Effect Transistors and Solar Cells”Self-Assembled Amphiphilic Diketopyrrolopyrrole-Based Oligothiophenes for Field-Effect Transistors and Solar Cells. Mei, J.; Graham, K. R.; Stadler, R.; Tiwari, S. P.; Cheun, H.; Shim, J.; Yoshio, M.; Nuckolls, C.; Kippelen, B.; Castellano, R. K.; Reynolds, J. R.* Chem. Mater. 2011, 23, 2285–2288.
2010Table of contents graphic for “Rapid Access to C3- and Cs-Symmetric AAT Organogelators via Ring Opening of a Common Benzotrifuranone Precursor”Rapid Access to C3- and Cs-Symmetric AAT Organogelators via Ring Opening of a Common Benzotrifuranone Precursor. Baker, M. B.; Yuan, L.; Marth, C. J.; Li, Y.; Castellano, R. K.* Supramol. Chem. 2010, 22, 789–802 (invited contribution to issue in memory of Prof. Dmitry M. Rudkevich).
2010Table of contents graphic for “Blue-Violet Electroluminescence from a Highly Fluorescent Purine”Blue-Violet Electroluminescence from a Highly Fluorescent Purine. Yang, Y.; Cohn, P.; Dyer, A. L.; Eom, S.-H.; Reynolds, J. R.*; Castellano, R. K.*; Xue, J.* Chem. Mater. 2010, 22, 3580–3582.
2010Table of contents graphic for “ACE2 Activation Promotes Antithrombotic Activity”ACE2 Activation Promotes Antithrombotic Activity. Fraga-Silva, R. A.; Sorg, B. S.; Wankhede, M.; deDeugd, C.; Jun, J. Y.; Baker, M. B.; Li, Y.; Castellano, R. K.; Katovich, M. J.; Raizada, M. K.*; Ferreira, A. J. Mol. Med. 2010, 16, 210–215 (manuscript selected for the journal cover art).
2009Table of contents graphic for “Benzotrifuranone: Synthesis, Structure, and Access to Polycyclic Heteroaromatics”Benzotrifuranone: Synthesis, Structure, and Access to Polycyclic Heteroaromatics. Li, Y.; Lampkins, A. J.; Baker, M. B.; Sumpter, B. G.; Huang, J.; Abboud, K. A.; Castellano, R. K.* Org. Lett. 2009, 11, 4314–4317.
2009Table of contents graphic for “Evidence for Angiotensin Converting Enzyme 2 as a Therapeutic Target for the Prevention of Pulmonary Hypertension”Evidence for Angiotensin Converting Enzyme 2 as a Therapeutic Target for the Prevention of Pulmonary Hypertension. Ferreira, A. J.; Shenoy, V.; Yamazato, Y.; Sriramula, S.; Francis, J.; Yuan, L.; Castellano, R. K.; Ostrov, D. A.; Oh, S. P.; Katovich, M. J.; Raizada, M. K.* Am. J. Resp. Care and Med. 2009, 179, 1048–1054 (manuscript selected for the journal cover art).
2009Table of contents graphic for “Synthesis, Photophysical Behavior, and Electronic Structure of Push–Pull Purines”Synthesis, Photophysical Behavior, and Electronic Structure of Push–Pull Purines. Butler, R. S.; Cohn, P.; Tenzel, P. A.; Abboud, K. A.; Castellano, R. K.* J. Am. Chem. Soc. 2009, 131, 623–633.
2008Table of contents graphic for “Links Between Through-Bond Interactions and Assembly Structure in Simple Piperidones”Links Between Through-Bond Interactions and Assembly Structure in Simple Piperidones. Yuan, L.; Sumpter, B. G.; Abboud, K. A.; Castellano, R. K.* New J. Chem. 2008, 32, 1924–1934 (identified as a “hot article”).
2008Table of contents graphic for “Structure-based Identification of Small Molecule ACE2 Activators as Novel Antihypertensives”Structure-based Identification of Small Molecule ACE2 Activators as Novel Antihypertensives. Hernández Prada, J. A.; Ferreira, A. J.; Katovich, M. J.; Shenoy, V.; Qi, Y.; Santos, R. A. S.; Castellano, R. K.; Lampkins, A. J.; Gubala, V.; Ostrov, D. A.*; Raizada M. K.* Hypertension 2008, 51, 1312–1317 (manuscript selected as the cover photo).
2008Table of contents graphic for “Assessable Consequences of Donor-σ-Acceptor Interactions in β-Aminoketones”Assessable Consequences of Donor-σ-Acceptor Interactions in β-Aminoketones. Lampkins, A. J.; Li, Y.; Al Abbas, A.; Abboud, K. A.; Ghiviriga, I.; Castellano, R. K.* Chem. Eur. J. 2008, 14, 1452–1463.
2007Table of contents graphic for “A New Class of Supramolecular Wires”A New Class of Supramolecular Wires. Sumpter, B. G.*; Meunier, V.; Valeev, E. F.; Lampkins, A. J.; Li, H.; Castellano, R. K.* J. Phys. Chem. C. 2007, 111, 18912–18916.
2007Table of contents graphic for “Investigation of the Nanoscale Self-Assembly of Donor-σ-Acceptor Molecules”Investigation of the Nanoscale Self-Assembly of Donor-σ-Acceptor Molecules. Sumpter, B. G.*; Meunier, V.; Vázquez-Mayagoitia, Á.; Castellano, R. K. Int. J. Quantum Chem. 2007, 107, 2233–2242.
2007Table of contents graphic for “Highly Fluorescent Donor–Acceptor Purines”Highly Fluorescent Donor–Acceptor Purines. Butler, R. S.; Myers, A. K.; Bellarmine, P.; Abboud, K. A.; Castellano, R. K.* J. Mater. Chem. 2007, 17, 1863–1865 (invited contribution to the 2007 “Emerging Investigators” issue).
2006Table of contents graphic for “Self-Complementary Purines By Quadruple Hydrogen Bonding”Self-Complementary Purines By Quadruple Hydrogen Bonding. Martin, A. M.; Butler, R. S.; Ghiviriga, I.; Giessert, R. E.; Abboud, K. A.; Castellano, R. K.* Chem. Commun. 2006, 4413–4415.
2006Table of contents graphic for “Remote Asymmetric Induction About a Crowded Aromatic Core”Remote Asymmetric Induction About a Crowded Aromatic Core. Lampkins, A. J.; Abdul-Rahim, O.; Castellano, R. K.* J. Org. Chem. 2006, 71, 5815–5818.
2005Table of contents graphic for “Enhanced Small-Molecule Assembly through Directional Intramolecular Forces”Enhanced Small-Molecule Assembly through Directional Intramolecular Forces. Lampkins, A. J.; Abdul-Rahim, O.; Li, H.; Castellano, R. K.* Org. Lett. 2005, 7, 4471–4474.
2005Table of contents graphic for “Synthesis and Self-Assembly of Functionalized Donor-σ-Acceptor Molecules”Synthesis and Self-Assembly of Functionalized Donor-σ-Acceptor Molecules. Li, H.; Homan, E. A.; Lampkins, A. J.; Ghiviriga, I.; Castellano, R. K.* Org. Lett. 2005, 7, 443–446.
2004Table of contents graphic for “Progress Toward Understanding the Nature and Function of C-H···O Interactions”Progress Toward Understanding the Nature and Function of C-H···O Interactions. Castellano, R. K.* Curr. Org. Chem. 2004, 8, 845–865.
2003Table of contents graphic for “Interactions with Aromatic Rings in Chemical and Biological Recognition”Interactions with Aromatic Rings in Chemical and Biological Recognition. Meyer, E. A.; Castellano, R. K.*; Diederich, F.* Angew. Chem. Int. Ed. 2003, 42, 1210–1250 (top 20 most cited article in Angewandte Chemie since 2003; identified as the “Best Review of 2003” by the German Chemical Society).

Postdoctoral, Graduate, and Undergraduate Work

YearPublication
2004H-bonded Complexes of Adenine with Rebek Imide Receptors Are Stabilized by Cation-π Interactions and Destabilized by Stacking with Perfluoroaromatics. Faraoni, R.; Castellano, R. K.; Gramlich, V.; Diederich, F.* Chem. Commun. 2004, 370–371.
2002De Novo Design, Synthesis, and In Vitro Evaluation of Inhibitors for Prokaryotic tRNA-Guanine Transglycosylase: A Dramatic Sulfur Effect on Binding Affinity. Meyer, E. A.; Brenk, R.; Castellano, R. K.; Furler, M.; Klebe, G.*; Diederich, F.* ChemBioChem 2002, 3, 250–253.
2002Rebek Imides and Their Adenine Complexes: Hoogsteen Preferences in the Solid State and in Solution. Castellano, R. K.; Gramlich, V.; Diederich, F.* Chem. Eur. J. 2002, 8, 118–129.
2001Remarkable Spectator Ligand Effect on the Rate Constant of Ligand Substitution of (Aqua)ruthenium(II) Complexes. Huynh, M. H. V.*; Lasker, J. M.; Wetzler, M.; Mort, B.; Szczepura, L. F.*; Witham, L. M.; Cintron, J. M.; Marschilok, A. C.; Ackerman, L. J.; Castellano, R. K.; Jameson, D. L.*; Churchill, M. R.; Jircitano, A. J.; Takeuchi, K. J.* J. Am. Chem. Soc. 2001, 123, 8780–8784.
2000Emergent Mechanical Properties of Self-Assembled Polymeric Capsules. Castellano, R. K.; Clark, R.; Craig, S. L.; Nuckolls, C.; Rebek, J., Jr.* Proc. Natl. Acad. Sci. U.S.A. 2000, 97, 12418–12421.
2000Detection and Mechanistic Studies of Multi-Component Assembly by Fluorescence Resonance Energy Transfer. Castellano, R. K.; Craig, S. L.; Nuckolls, C.; Rebek, J., Jr.* J. Am. Chem. Soc. 2000, 122, 7876–7882.
2000Reversibly-Formed Polymeric Capsules. Castellano, R. K.; Nuckolls, C.; Rebek, J., Jr.* Polym. News 2000, 25, 44–52.
1999Transfer of Chiral Information through Molecular Assembly. Castellano, R. K.; Nuckolls, C.; Rebek, J., Jr.* J. Am. Chem. Soc. 1999, 121, 11156–11163.
1999Hierarchy of Order in Liquid Crystalline Polycaps. Castellano, R. K.; Nuckolls, C.; Eichhorn, S. H.; Wood, M. R.; Lovinger, A. J.; Rebek, J., Jr.* Angew. Chem. Int. Ed. 1999, 38, 2603–2606.
1999Investigating Molecular Recognition by Mass Spectrometry: Characterization of Calixarene-Based Self-Assembling Capsule Hosts with Charged Guests. Schalley, C. A.; Castellano, R. K.; Brody, M. S.; Rudkevich, D. M.; Siuzdak, G.; Rebek, J., Jr.* J. Am. Chem. Soc. 1999, 121, 4568–4579.
1998Formation of Discrete, Functional Assemblies and Informational Polymers Through the Hydrogen Bonding Preferences of Calixarene Aryl and Sulfonyl Tetraureas. Castellano, R. K.; Rebek, J., Jr.* J. Am. Chem. Soc. 1998, 120, 3657–3663.
1998Synthesis of Some Cobaloxime Derivatives: A Demonstration of “Umpolung” in the Reactivity of an Organometallic Complex. Jameson, D. L.*; Grzybowski, J. J.*; Hammels, D. E.; Castellano, R. K.; Hoke, M. E.; Freed, K.; Basquill, S.; Mendel, A.; Shoemaker, W. J. J. Chem. Educ. 1998, 75, 447–450.
1998Tris[N-(3-tert-butyl)pyrazolyl]methane. Reger, D. L.*; Collins, J. E.; Jameson, D. L.; Castellano, R. K.; Canty, A. J.; Jin, H. Inorg. Synth. 1998, 32, 63–65.
1998Poly(1-pyrazolyl)alkane Ligands. Jameson, D. L.*; Castellano, R. K.; Reger, D. L.; Collins, J. E.; Tolman, W. B.; Tokar, C. J. Inorg. Synth. 1998, 32, 51–63.
1997Polycaps: Reversibly Formed Polymeric Capsules. Castellano, R. K.; Rudkevich, D. M.; Rebek, J., Jr.* Proc. Natl. Acad. Sci. U.S.A. 1997, 94, 7132–7137.
1997Chiral Capsules: Asymmetric Binding in Calixarene-Based Capsules. Castellano, R. K.; Kim, B. H.; Rebek, J., Jr.* J. Am. Chem. Soc. 1997, 119, 12671–12672.
1996Tetramethoxy Calix[4]arenes Revisited: Conformational Control Through Self-Assembly. Castellano, R. K.; Rudkevich, D. M.; Rebek, J., Jr.* J. Am. Chem. Soc. 1996, 118, 10002–10003.
1996Crystal and Molecular Structure of the Bidentate Ligand 2,2-Di(1-pyrazolyl)propane, CH3C(C3N2H3)2CH3. Churchill, M. R.*; Churchill, D. G.; Huynh, M. H. V.; Takeuchi, K. J.; Castellano, R. K.; Jameson, D. L. J. Chem. Cryst. 1996, 26, 179–183.
1996Crystal and Molecular Structure of Di(1-pyrazolyl)methane, CH2(C3N2H3)2. Churchill, M. R.*; Churchill, D. G.; Huynh, M. H. V.; Takeuchi, K. J.; Castellano, R. K.; Jameson, D. L. J. Chem. Cryst. 1996, 26, 93–97.

Patents

YearPatent
2026Novel Small Molecule Anticancer Agents, Combinations and Uses Thereof. Brian K. Law, Ronald K. Castellano, Elham Yaaghubi, and Stephen C. Jahn. US Patent No. 12,721,833, issued September 1, 2026.
2024Novel Small Molecule Anticancer Agents, Combinations and Uses Thereof. Brian K. Law and Ronald K. Castellano. US Patent No. 12,030,864, issued July 9, 2024.
2020Additional Novel Small Molecule Anticancer Agents. Brian K. Law, Ronald K. Castellano, and Renan B. Ferreira. US Patent No. 10,813,904, issued October 27, 2020.
PendingAnticancer Compounds and Uses Thereof. Brian K. Law and Ronald K. Castellano. US application 18/271,584, patent pending.

Compiled from the group’s records, September 2026. Titles link to the publisher via DOI. An asterisk (*) marks a corresponding author; a dagger (†) marks authors who contributed equally.